Piles vs. Rectal Cancer: Know the Truth Are piles a cause of rectal cancer? The short answer is no. However, rectal cancer can often cause secondary piles to develop. Here more from Dr. Krunal Khobragade, Consultant Surgical Oncologist from HCG, Nagpur. If you have piles,especially as you get older—don’t just treat the symptoms. Consult a doctor for a colonoscopy or sigmoidoscopy to rule out any underlying concerns. Early screening is the most effective way to ensure your long-term health. Watch