Xalnesiran, a small interfering RNA molecule that targets a conserved region of the hepatitis B virus (HBV) genome and silences multiple HBV transcripts, may have efficacy, with or without an ...
Cell-free DNA (cfDNA) sequence analysis to screen for fetal aneuploidy can incidentally detect maternal cancer. Additional data are needed to identify DNA-sequencing patterns and other biomarkers ...
The Sepsis-1, Sepsis-2, and Sepsis-3 definitions are for adult sepsis. The IPCC (International Pediatric Sepsis Consensus Conference) and Phoenix definitions are for pediatric sepsis. ARDS denotes ...
Dr. Kathleen M. McFadden (Medicine): A 22-year-old woman was transferred to this hospital in the summer before the coronavirus disease 2019 pandemic because of headache, fever, and respiratory ...
Data are needed from randomized trials on a long-term antithrombotic treatment strategy for patients with atrial fibrillation and stable coronary artery disease. New research findings are ...
The efficacy of trastuzumab deruxtecan after endocrine-based therapy in patients with metastatic breast cancer with low expression of human epidermal growth factor receptor 2 is unknown.
A woman with TEMPI syndrome who had a second relapse after many years of disease control with myeloma-type therapy had a rapid response to teclistamab, a bispecific antibody targeting plasma cells.
The authors describe the science behind a clinical trial of a combination of therapies, including xalnesiran, to treat chronic hepatitis B virus infection. This editorial was updated on December 5 ...
Somatic monoallelic single nucleotide variants in the genes that encode isocitrate dehydrogenase (IDH) 1 and 2 are found in a large subset of diffusely infiltrating gliomas and subsets of acute ...
For patients with chronic hepatitis B virus infection, standard care involves lifelong treatment and rarely leads to functional cure. New research findings on the investigational antiviral agent ...
Andrew Hantel is an assistant professor of medicine at Harvard Medical School and a faculty member in the Divisions of Leukemia and Population Sciences at Dana-Farber Cancer Institute and at the ...