EMBO Press21h
Getting to the heart of cardiovascular complications associated with inflammatory arthritis
Inflammatory arthritis encompasses a group of autoimmune diseases, including rheumatoid arthritis (RA), psoriatic arthritis ...
EMBO Press2d
Metabolic reaction fluxes as amplifiers and buffers of risk alleles for coronary artery disease
Using genetically predicted metabolic reaction fluxes, the authors identify reactions that can amplify or buffer the effect ...
EMBO Press4d
Mouse promoters are characterised by low occupancy and high turnover of RNA polymerase II
Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results ...
The EMBO Journal4d
HAND1 level controls the specification of multipotent cardiac and extraembryonic progenitors from human pluripotent stem cells
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Diverse sets of progenitors contribute to the ...
The EMBO Journal4d
SIRT5-mediated desuccinylation of PPA2 enhances HIF-1alpha-dependent adaptation to hypoxic stress and colorectal cancer metastasis
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Metastasis is the primary cause of death in ...
The EMBO Journal4d
Liver TET1 promotes metabolic dysfunction-associated steatotic liver disease
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Global hepatic DNA methylation change has been ...
The EMBO Journal7d
Praja2 controls P-body assembly and translation in glioblastoma by non-proteolytic ubiquitylation of DDX6
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Glioblastoma multiforme (GBM) is the most ...
EMBO Press7d
HDAC6 deacetylates ENKD1 to regulate mitotic spindle behavior and corneal epithelial homeostasis
HDAC6 is upregulated in corneal diseases and causes ENKD1 deacetylation at lysine 98. Deacetylation of ENKD1 blocks its ...
The EMBO Journal7d
Syndecans and glycosaminoglycans influence B-cell development and activation
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Syndecans (SDCs) are ...