Background: Subclinical hypothyroidism has been linked to adverse renal outcomes, but it is unknown whether treatment of subclinical hypothyroidism reduces the risk of these adverse outcomes. We ...

Key points Canada’s health systems are stressed with increasing demands for health care and services. The causes of this stress are multifactorial and include an aging population and a health ...

Key points The provision of health care is hard and, understandably, clinicians struggle. Beyond meaningful health care interactions, clinicians must also integrate large volumes of demographic, ...

Care should include explicit statements affirming patient choice. Clinicians with faith-based objections should provide timely, tolerant referral; judgmental or obstructive care may result in ...

Behavioural and psychological symptoms of dementia (BPSD) are common and negatively affect patient and caregiver outcomes Nearly all people living with dementia develop BPSD. 1 Symptoms vary over time ...

Background: The relation between emergency department opioid prescribing and subsequent harm is complex and poorly studied. We sought to quantify adverse outcomes, incremental risk, and rates of ...

KEY POINTS Physical activity is a modifiable risk factor for more than 30 chronic conditions relevant to the older adult; 150 minutes per week of moderate physical activity can reduce all-cause ...

Diet is associated with depressive symptoms A 2024 umbrella review — including nearly 10 million participants enrolled in observational studies — found that people who consumed more ultra-processed ...

KEY POINTS A 65-year-old woman presented to the emergency department with an 8-day history of progressive leg weakness and poor mobility in the setting of a known history of mixed neurogenic and ...

Background: The implementation and clinical impact of machine learning–based early warning systems for patient deterioration in hospitals have not been well described. We sought to describe the ...

Background: Cancer surveillance data are essential to help understand where gaps exist and progress is being made in cancer control. We sought to summarize the expected impact of cancer in Canada in ...

Polycystic ovarian syndrome (PCOS) is a chronic disorder associated with infertility; miscarriage; adverse pregnancy outcomes; and cardiovascular, metabolic, psychological and neoplastic risks.