Christian McCaffrey pulled up limping after taking a pitch early in their game against the Bills on Sunday night.

San Francisco 49ers running back Christian McCaffrey suffered an an apparent non-contact lower leg injury on Sunday Night ...

The Week 13 Sunday slate closes with the Buffalo Bills (9-2) hosting the San Francisco 49ers (5-6) on Sunday Night Football.

San Francisco 49ers running back and Stanford Cardinal legend Christian McCaffrey has not looked like himself since returning ...

Christian McCaffrey has been inefficient in his three games played since dealing with Achilles tendinitis. He doesn't look ...

The worst fears for the San Francisco 49ers and star Christian McCaffrey may have been realized, as the star running back ...

Christian McCaffrey and the 49ers travel to Buffalo to take on Josh Allen and the Bills for Sunday Night Football. Live ...

Even after Christian McCaffrey’s return to the field, the story surrounding his Achilles injury and the impact it’s having on ...

San Francisco 49ers RB Christian McCaffrey powers through for a 19-yard run against the team's Week 13 matchup against the ...

Christan McCaffrey appeared to come up limp and had to slide down without contact in the second quarter against the Bills. We ...

Christian McCaffrey was viewed as the savior for the San Francisco 49ers. His return was supposed to cure all of the ...

The San Francisco 49ers didn’t have many changes to their Thursday practice participation report.