The Buffalo Bills (9-2) bring a six-game winning streak into a matchup with the San Francisco 49ers (5-6) on Sunday, December ...

In last week’s 38-10 blowout loss to the Green Bay Packers, the 49ers’ loss had little to do with the weather at Lambeau ...

The 49ers listed Brock Purdy as a limited participant while Nick Bosa and Trent Williams were among those not practicing ...

The Buffalo Bills Sunday night game against the San Francisco 49ers is shaping up to be a weather game as bitter cold air ...

You can listen on SiriusXM satellite radio on channel 225 (Bills feed) and channel 226 (49ers feed), and on traditional radio ...

Buffalo Bills linebacker Matt Milano has missed the first 11 games of the 2024 season with a bicep injury. Will he return ...

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on "Sunday Night Football" in Week 13. The ...

See who's in and who's out for the Week 13 matchup between the Buffalo Bills and San Francisco 49ers on December 1, 2024.

Buffalo Bills Coach Sean McDermott discusses winter weather ahead of their matchup against the San Francisco 49ers this ...

Watch out for the tables on "Sunday Night Football." The nightcap of Sunday's action will be in northern New York with the ...

While the 49ers look like an easy opponent, San Francisco's health could be a major factor in the game, warns one NFL expert.

The 49ers travel to Buffalo to take on the AFC East-leading Buffalo Bills. Check out our best bet for the game ...