The hippocampus follows a "tabula plena" model, starting with dense, random connections that are pruned into an efficient ...

The hippocampus is a key brain region involved in memory formation and spatial orientation. It transforms short-term memories ...

The hippocampus is a key brain region involved in memory formation and spatial orientation. It transforms short-term memories into long-term ones, helping us retain and build upon our experiences.

Adolescence is widely thought to be a time when the brain trims away excess neural connections, refining circuits through synaptic pruning. New research now suggests this view may be incomplete.

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Scientists used a tool called SynTrogo to edit brain circuits in mice, showing that trimming select synapses can make ...

Researchers developed SynTrogo, a molecular tool enabling targeted synapse removal via engineered neuron–astrocyte ...

For the first time, researchers have confirmed that selectively pruning certain synapses in the brain can paradoxically ...

Findings underpin the scientific rationale for Anavex’s targeted autophagy approach with orally administered blarcamesineConvergence of impaired ...

A human infant is born with roughly twice as many synapses as it will eventually need. Over the first few years of life, the ...