A sweeping storm system moving across the U.S. threatens to bring tornadoes, blizzards and possibly wildfires to different regions of the country.

A powerful storm system that unleashed severe weather for millions of Americans from coast to coast this week is now taking aim at the nation’s midsection, bringing blizzard conditions to the northern Plains, thunderstorms and the threat of tornadoes to the Midwest and South and an elevated risk of wildfires to the southern Plains.

The forecast comes days after an expansive storm similarly trekked across the U.S. last week, unloading snow in the northern Plains and bringing tornadoes and wildfires to the South. At least five storm-related deaths in Nebraska and Mississippi were tied to that storm.