Severe hypothyroidism is associated with a high burden of systolic/diastolic ventricular dysfunction and myocardial deformation abnormalities.
Background Although the increased risk of cardiovascular disease in patients with SLE is well-documented, effective tools for risk stratification remain elusive. This study sought to explore the ...
BACKGROUND: Right ventricular failure drives both morbidity and mortality in pulmonary arterial hypertension (PAH), but the mechanism of transition from compensated right ventricle (cRV) to ...
Reduced progression of myocardial fibrosis measured by LGE on cardiac MRI (p=0.022)Significant improvement in LVEF versus placebo in patients with baseline cardiomyopathy (p=0.017)Global Statistical ...
The arterial vasculature is the second most frequently calcified structure in the human body after the skeleton. Calcification of the aorta and aortic valves occurs in most individuals in westernized ...
Objective: To obtain the derived parameter left atrial stiffness index (LASI) using two-dimensional speckle tracking imaging (2D-STI) and evaluate the diagnostic value o ...
New analyses out to 24-months showed improvement in heart and lung function compared to expected declines in DMD natural history - - Data expand on previously reported results demonstrating that z-ros ...
Higher blood levels of allergy molecule IgE were associated with worsening right heart function in people with PAH, a study ...
SGT-003 in the INSPIRE DUCHENNE trial to date - - Robust microdystrophin expression with consistent mechanistic evidence of dystrophin associated protein complex (DAPC) restoration and improvements in ...
SGT-003 in the INSPIRE DUCHENNE trial to date - - Robust microdystrophin expression with consistent mechanistic evidence of dystrophin associated protein complex ...
Children born with single‑ventricle heart disease, a rare and serious heart defect, often undergo multiple surgeries in their first years of life.
Background Pharmacotherapy combinations have been shown to improve survival and reduce hospitalisations in adults with ...