Derrick Henry Kansas City Chiefs

Chiefs vs Colts betting line & prediction

Titans at Chiefs predictions for AFC championship game in Kansas City

Who has the edge when the Titans (11-7) head to Kansas City to face the Chiefs (13-4) in the AFC championship game Sunday (2:05 p.m., CBS)?

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Who is favored to win in Indianapolis Colts vs. Kansas City Chiefs? NFL predictions, picks in Week 12

USA TODAY Touchdown Wire on MSN · 1d

4 things to know and a prediction for Colts vs. Chiefs Week 12 game

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Chiefs vs. Colts 2025 Prediction, Odds, Picks - Nov 23

The Kansas City Chiefs (5-5) are favored by 3.5 points against the Indianapolis Colts (8-2) on November 23, 2025, starting at 1 p.m. ET, airing on CBS.

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Chiefs vs. Colts best bets, picks and odds | Week 12 2025

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Chiefs face crucial test vs. Colts on Sunday as Patrick Mahomes looks to avoid rare third straight loss

5hon MSN

NFL DFS Week 12 Optimal Lineup: Vintage Patrick Mahomes, Derrick Henry on tap

Create the best lineup on DraftKings for Sunday’s NFL Main Slate of games and take home the million-dollar first prize.

BND

Chiefs’ inability to contain Titans running back Derrick Henry contributes to loss

The outcome was still in doubt, but the Kansas City Chiefs knew they had a major problem on their hands entering the second half of Sunday’s game against the Tennessee Titans. And knowing and addressing the issues are two very different things.

Sports Illustrated

Chiefs' Super Bowl Ambitions Hinge on Derailing Titans RB Derrick Henry

The Kansas City defense must buckle down against a Tennessee offense led by powerful RB Derrick Henry and play-action of QB Ryan Tannehill The Tennessee Titans leaned heavily on their running game through their first two playoff wins, piling up 418 yards ...

1don MSN

NFL bold predictions for Week 12

The NFL got plenty of surprises last week, but perhaps none was more shocking than the Kansas City Chiefs losing a must-win game to stay in contention for the AFC West to the Denver Broncos in Week 11.