Defensive lineman Mykel Williams, the 49ers’ first-round pick, might have torn his ACL during win over the New York Giants.

By the fourth quarter of Sunday's 26-15 loss to the Houston Texans, San Francisco 49ers All-Pro left tackle Trent Williams ...

Trent Williams made sure to congratulate Brian Robinson Jr. after his first touchdown with the 49ers in Sunday’s win over the New York Giants.

The San Francisco 49ers receive a strong message from veteran Trent Williams ahead of the NFL trade deadline on November 4.

Left tackle Trent Williams is heading to his offseason home of Houston this week to lead the 49ers (5-2) against the Texans ...

But, aside from their record, there's another feat that the two NFC powerhouses have in common. Trent Williams and Brandon ...

In the late third and early fourth quarter and the Giants within 20-10, quarterback Mac Jones hit Kendrick Bourne for a ...

Jones didn't miss a pass in the first half and improved to 5-2 as a starter this season, as Brock Purdy nears his return from ...

The San Francisco 49ers have lost many players to injury this season, but they still have three who are considered among the ...

Quarterback Brock Purdy will miss his fourth straight game for the San Francisco 49ers because of a toe injury.

Quarterback Brock Purdy remains limited by a toe injury and could miss his fourth straight game for the San Francisco 49ers.

The NFL fined 49ers left tackle Trent Williams $11,593 for unnecessary roughness in San Francisco's Week 6 loss to the Tampa ...