Most rotator-cuff tears are degenerative, atraumatic, and more prevalent with age. Nonoperative treatment, including physical ...
Xalnesiran, a small interfering RNA molecule that targets a conserved region of the hepatitis B virus (HBV) genome and silences multiple HBV transcripts, may have efficacy, with or without an ...
Cell-free DNA (cfDNA) sequence analysis to screen for fetal aneuploidy can incidentally detect maternal cancer. Additional data are needed to identify DNA-sequencing patterns and other biomarkers ...
The Sepsis-1, Sepsis-2, and Sepsis-3 definitions are for adult sepsis. The IPCC (International Pediatric Sepsis Consensus Conference) and Phoenix definitions are for pediatric sepsis. ARDS denotes ...
Dr. Kathleen M. McFadden (Medicine): A 22-year-old woman was transferred to this hospital in the summer before the coronavirus disease 2019 pandemic because of headache, fever, and respiratory ...
Nivolumab, a PD-1 inhibitor, and ipilimumab, a cytotoxic T-lymphocyte antigen 4 inhibitor, are immune checkpoint inhibitors with complementary mechanisms of action, which might enhance antitumor ...
Dr. Lara Basovic: A 41-year-old man was admitted to the epilepsy monitoring unit (EMU) of this hospital because of seizures. When the patient was 4 years of age, his mother noticed an episode of ...
Twice-yearly subcutaneous lenacapavir has been shown to be efficacious for prevention of HIV infection in cisgender women. The efficacy of lenacapavir for preexposure prophylaxis (PrEP) in ...
Panel A is a map of the communes in Nha Trang showing the trial-group assignment in each commune (no vaccination, 0p+1, 1p+1, 2p+1, or 3p+0). Panel B shows the percentages of infants (children 4 ...
The authors describe the science behind a clinical trial of a combination of therapies, including xalnesiran, to treat chronic hepatitis B virus infection. This editorial was updated on December 5 ...
A woman with TEMPI syndrome who had a second relapse after many years of disease control with myeloma-type therapy had a rapid response to teclistamab, a bispecific antibody targeting plasma cells.