The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

Christian McCaffrey pulled up limping after taking a pitch early in their game against the Bills on Sunday night.

San Francisco 49ers running back Christian McCaffrey was running wild against the Buffalo Bills on Sunday Night Football.

Dec 1, 2024; Orchard Park, New York, USA; San Francisco 49ers running back Christian McCaffrey (23) tries to avoid Buffalo ...

According to head coach Kyle Shanahan, running back Christian McCaffrey suffered a potentially season-ending PCL injury in ...

Allen had touchdowns passing, rushing and receiving, becoming the first quarterback and seventh player in the Super Bowl era ...

San Francisco coach Kyle Shanahan told reporters postgame that their star running back had injured the posterior cruciate ...

RB Christian McCaffrey, playing in just his fourth game since returning from Achilles tendinitis, suffered a PCL injury ...

San Francisco 49ers running back Christian McCaffrey left Sunday night's contest versus the Buffalo Bills with what the team ...

San Francisco 49ers running back Christian McCaffrey could be done for the season after just four games. As head coach Kyle ...

San Francisco 49ers running back Christian McCaffrey suffered another injury in just his fourth game of the season. During ...

Christan McCaffrey appeared to come up limp and had to slide down without contact in the second quarter against the Bills. We ...