The four-time defending AFC Champs squared off against the Detroit Lions in one of a number of Thanksgiving matchups between ...

You can listen on SiriusXM satellite radio on channel 225 (Bills feed) and channel 226 (49ers feed), and on traditional radio ...

The NFL star Buffalo Bills quarterback is a 6-foot-5 mountain of a man. For two kids given a dream come true, one of them ...

With the Bills (9-2) on the cusp of a fifth straight AFC East division title, the pressure is on Allen and Co. to deliver the ...

Buffalo Bills quarterback Josh Allen and coach Sean McDermott reacted to forecasts of a snow game against the San Francisco ...

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on “Sunday Night Football” in Week 13. The ...

Simpson carried the ball 29 times against the Lions and set a new NFL record with 273 rushing yards, breaking his own record ...

The Buffalo Bills look set to face the San Francisco 49ers in wild conditions with heavy snow continuing to fall in the area ...

San Francisco 49ers defensive end Nick Bosa missed Wednesday's practice as the team began preparations for Sunday's game ...

Now that the holiday season is in full swing, several Bills players are taking the time to be active in the community. A ...

One of the top receivers in the league will be featured when George Kittle and the San Francisco 49ers visit the Buffalo ...

San Francisco 49ers star Deebo Samuel had a blunt reaction when asked about his low numbers to begin this season.