The Kansas City Chiefs absolutely need to beat the Indianapolis Colts in Week 12 to keep their playoff chances alive.

You've seen the model's best bets for Indianapolis Colts vs. Kansas City Chiefs. Now, get against the spread, total and money-line picks for every Week 12 NFL game here, all from the model that's simulated every game 10,000 times.

The Indianapolis Colts are on the road to take on the Kansas City Chiefs in week 12 of the 2025 season, kickoff is at 1:00 p.m. EST. Fresh off of their bye the Colts travel to take on the 5-5 Chiefs.

The Chiefs season is hanging in the balance and Sunday’s game has not gotten off to a good start for Kansas City.

The Indianapolis Colts couldn't ask for a better inactive list ahead of a big-time battle with the Kansas City Chiefs.

Thornton is on track for a bigger role against the Colts, per CBS Sports' Tracy Wolfson. The former Patriots speedster was much more involved at the start of the season, when he peaked with nine catches for 71 yards and a touchdown during the Chiefs' late-September win over the Giants.

It would be difficult to find a more surprising NFL team this season than the Indianapolis Colts. Part of their success has been the revival of quarterback Daniel Jones’ career, but a lot of it also has to do with their stacked defense,

The Kansas City Chiefs' offense has raised some alarming questions that it needs to answer against the Indianapolis Colts in Week 12.