Christian McCaffrey pulled up limping after taking a pitch early in their game against the Bills on Sunday night.

San Francisco 49ers running back Christian McCaffrey suffered an an apparent non-contact lower leg injury on Sunday Night Football vs. the Buffalo Bills.

The worst fears for the San Francisco 49ers and star Christian McCaffrey may have been realized, as the star running back exited Sunday’s snowy game in Buffalo with a non-contact injury.

Christan McCaffrey appeared to come up limp and had to slide down without contact in the second quarter against the Bills. We’ll update the injury information as it comes in

Christian McCaffrey has been inefficient in his three games played since dealing with Achilles tendinitis. He doesn't look anywhere close to the player that he

Even after Christian McCaffrey’s return to the field, the story surrounding his Achilles injury and the impact it’s having on the field isn’t lining up, whether it’s the story from him or the San Francisco 49ers.

The San Francisco 49ers are up against the Buffalo Bills in Week 13. The 49ers have dealt with an array of injuries this season, and they enter game week with a 5-6 record.

The San Francisco 49ers didn't have many changes to their Thursday practice participation report. One big difference between Wednesday and Thursday though was Christian McCaffrey's return to practice after sitting out Wednesday's session.

Christian McCaffrey is deadly serious about his 9-to-5 job — head coach Kyle Shanahan calls him “a psycho in the best way possible” — but he loosens up with reporters when the topic isn’t tied to his NFL career.

San Francisco 49ers running back Christian McCaffrey didn't hide his disappointment after Sunday's crushing loss to the Green Bay Packers. Despite