San Francisco 49ers running back Christian McCaffrey bulldozes a Buffalo Bills defender into to the snowy gridiron during a 20-yard run.

The Bills return from their bye and will look to keep pace with the Kansas City Chiefs at the top of the AFC. Josh Allen has ...

San Francisco 49ers running back Christian McCaffrey suffered another injury in just his fourth game of the season. During ...

Dec 1, 2024; Orchard Park, New York, USA; San Francisco 49ers running back Christian McCaffrey (23) tries to avoid Buffalo ...

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

San Francisco 49ers running back Christian McCaffrey is questionable to return to Sunday night's game against the Buffalo Bills with a knee injury.

After missing the first eight games of the season with bilateral Achilles tendinitis, San Francisco star running back ...

McCaffrey slid down untouched in the backfield after taking a toss, then immediately went to the 49ers’ medical tent and ...

Christian McCaffrey was off to a great start in Sunday night’s matchup with the Bills but had to exit the contest early in the second quarter.

Achilles tendinitis robbed San Francisco 49ers star Christian McCaffrey of the first eight games of the 2024 NFL season. A ...

Christian McCaffrey pulled up limping after taking a pitch early in their game against the Bills on Sunday night.

Christan McCaffrey appeared to come up limp and had to slide down without contact in the second quarter against the Bills. We ...