Peroxiredoxins are among the most abundant enzymes involved in managing oxidative stress. They control the levels of peroxides such as hydrogen peroxide, relay redox signals, and help protect other ...

Researchers have found hundreds of metabolic enzymes attached to human DNA inside the cell nucleus. Different tissues and cancers show unique patterns of these enzymes, forming a “nuclear metabolic ...

Chemists have developed a light-driven method for producing a rare and highly strained molecular structure known as “housane.” Designing a new drug often starts with a basic but difficult task: making ...

Researchers simulated nearly every molecule in a bacterial cell — and then watched the cell grow and reproduce.

Complementary biochemical and structural findings reveal molecular principles underlying substrate selectivity by a model hyaluronan synthase.

NAEs are lipid-based endogenous signaling molecules that are produced by combining long-chain fatty acids with ethanolamine. Collectively, NAEs include both endocannabinoids and structurally related ...

Objectives Parkinson’s disease (PD) is a complex, progressive neurological disorder with motor and non-motor symptoms. Among the non-motor symptoms, constipation severely affects the patients’ quality ...