With only a few weeks left on the college football slate, NFL draft season is beginning to hit its stride. Before the San Francisco 49ers meet the Buffalo Bills in Week 13, USA TODAY’s NFL Draft Wire released their latest predictions for the 2025 draft with a new mock draft.

The 49ers have dealt with injuries to key players all season. Brandon Aiyuk injured his knee, Brock Purdy missed last week's game, and Fred Warner has a lingering ankle issue.

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on "Sunday Night Football" in Week 13. The Bills (9-2) are looking to build on a six-game win streak, while the 49ers (5-6) have lost their last two.

What to expect from Sunday Night Football's 49ers vs. Bills matchup. This is one of those games that feels like Buffalo's to lose. The Bills are 9-2, sitting at the top of the AFC

We thought San Francisco was poised for a massive second-half run after the Week 9 bye with Christian McCaffrey back, but the 49ers haven't looked good over their last three contests.  It wasn't a surprise the 49ers fell to the Green Bay Packers on Sunday with so many key contributors out.

San Francisco 49ers star linebacker Fred Warner revealed Wednesday that he has been playing through a broken bone in his ankle since September.

The Buffalo Bills are fresh off of their bye week heading into a Sunday Night Football matchup with the San Francisco 49ers, who are in serious danger of missin

The Dolphins defense has been a bright spot so far in 2024 and this offseason they are predicted to add a key piece from the NFC.

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The San Francisco 49ers face a tough challenge on Sunday, traveling to Wisconsin to take on the Green Bay Packers.