Preview the April 23 matchup between the Toronto Blue Jays and Houston Astros with odds over/under, game spread, betting lines and more.

Following a loss to the Houston Astros on Tuesday, the Toronto Blue Jays have started the season at 12-12 through their first 24 games of the 2025 season. After a good start, Toronto finds itself in third place in the AL East division behind the New York Yankees and Boston Red Sox.

Zach Dezenzo led the way for Houston with three hits. Christian Walker and Yainer Díaz had two hits apiece, including a homer for the former and a triple for the latter. Ryan Gusto (3-1, 2.78) also came one out from his first ever Quality Start, striking out six over 5 2 ⁄ 3 innings. He gave up one run on three hits and a walk.