Wildlife officials in the U.S. and Canada report cases of chronic wasting diseases where it hasn't been detected before.

Surface features of human prions responsible for their replication in the brain have been identified for the first time, which may provide key information into treatments of neurodegenerative diseases ...

Chronic wasting disease is contagious and relentless. There is no cure, no way to test living animals, and once infections are introduced into wild populations, there is no realistic way to stop them ...

The National Prion Disease Pathology Surveillance Center (NPDPSC) at Case Western Reserve University will receive up to $20 million in funding as part of a grant renewal from the Centers for Disease ...

Prion diseases are a family of rare progressive neurodegenerative disorders that affect both humans and animals. They are associated with the formation of aggregates of the prion protein, PrP. How ...

Affecting both people and animals, prion diseases are degenerative brain disorders that can debilitate or kill their victims. The most common form of prion disease affecting humans is sporadic ...

New research from Japan suggests that a rare brain-destroying disease caused by rogue prion proteins may be becoming more common—likely due to an aging population. The study, published last month in ...

Prion diseases are slow degenerative brain diseases that occur in people and various other mammals. No vaccines or treatments are available, and these diseases are almost always fatal. Scientists have ...

Prion protein, notorious for causing the brain-wasting mad cow and Creutzfeldt-Jakob diseases, may also be a coconspirator in Alzheimer’s disease, a new study in mice suggests. In mad cow and ...

A substantial species barrier prevents chronic wasting disease (CWD), a cervid prion disease with unknown zoonotic potential, from being transmitted to humans, new NIH data suggested. Healthy human ...

Many neurodegenerative diseases involve a common pattern of protein misfolding, aggregation, and toxicity. Though the identity of the actual polypeptide varies for each disease, the outcome converges ...

Familial human prion diseases are passed within families and are associated with 34 known prion protein mutations. To determine whether three of the unstudied mutations are transmissible, scientists ...