This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Neoadjuvant therapy in resectable small-cell lung cancer: A systematic review and meta-analysis. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not include a ...

As a general rule, the treatment of hyponatremia should be directed at the primary underlying disorder because such treatment might, in itself, correct the electrolyte imbalance. Thiazide diuretics ...

Paraneoplastic syndromes are rare groups of symptoms that affect some people with cancer. These symptoms aren’t directly caused by the spread of cancer but by: hormones and signaling molecules ...

Diane was brought to the emergency department via ambulance from home where her husband called 911 because she was acting strangely. According to Diane’s husband, she was intermittently acting ...

Dear Dr. Roach: My mother’s blood test has a sodium level of 130 mEq/L. She is not on diuretics, and she does not have heart or kidney problems. She is on thyroid medication and omeprazole. Do I need ...

Antidepressant for neuropathy pain leads to hyponatremia An older male patient started antidepressants for neuropathy pain but developed hyponatremia as a result. A 72-year-old patient with chronic ...

Paraneoplastic syndromes are a group of symptoms that happen in some people who have small-cell lung cancer (SCLC). Some paraneoplastic syndromes affect your nervous system, including your brain, ...