Studies have suggested a significant relationship between obesity or being overweight and the likelihood of developing autoimmune disorders. This association can be explained from an immunological ...

Regulatory T cells protect the body from misdirected or overly excited immune responses. A new study highlights previously unknown characteristics of these cells that could guide the development of ...

Every day, your immune system performs a delicate balancing act, attacking harmful invaders while protecting your own tissues. When that balance breaks, infections can spread unchecked, or the body ...

Over four decades ago, a surprising observation hinted at a specialized T cell population capable of suppressing autoimmunity. Now known as regulatory T cells, or Tregs, these immune modulators are ...

Early thymic progenitor (ETP) cells, derived from hematopoietic stem cells in the bone marrow, enter the thymus at the cortical-medullary junction (CMJ), retaining multipotent differentiation ...

In a recent perspective review, researchers attempt to collate and discuss scientific knowledge on the concept of the ‘immune self’ and use raw T cell assays, nine amino-long pathogen-derived peptides ...

The immune system has evolved to mount immune responses against foreign pathogens and to remain silent against self-antigens. A balance between immunity and tolerance is required as any disturbance ...

TOPSHOT - (L-R) The portraits of Mary E Brunkow, Fred Ramsdell and Shimon Sakaguchi are displayed during a press conference where the winners of the 2025 Nobel Prize in Physiology or Medicine are ...

Multiple sclerosis (MS) is a chronic immune-mediated disease characterized by the destruction of myelin sheaths, neuroaxonal damage, glial cell activation and formation of demyelinated plaques in the ...