Levels of the enzyme HO-1, which protects against toxicity, are elevated in sickle cell disease patients, especially children ...

An imbalance in the gut microbiome, the group of bacteria and other microbes in the digestive tract, may drive chronic SCD ...

New research shows that giving opioids to pediatric patients with sickle cell disease within 60 minutes of ED arrival reduces hospitalization risk.

Living with sickle cell disease means living with unpredictability. At the heart of this condition is pain; pain that comes suddenly, lingers unexpectedly, and shapes daily life in ways outsiders ...

Sickle cell disease (SCD) is a genetic blood disorder that can cause severe episodes of intense pain due to blocked blood flow. While national guidelines recommend prompt opioid treatment, this study ...