It's been generally assumed that RNA molecules and proteins have only limited or transient interactions in cells, like when proteins that can bind to RNA molecules influence the translation of genes, ...

A new study on fatty acid acylation, or attachment, patterns onto proteins in Caenorhabditis elegans, a type of roundworm, provides a foundation for future discoveries around protein function and its ...

Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...

Exploring the post-translational modifications of a key protein in Parkinson's disease, researchers uncover potential pathways for future therapies in neurodegenerative diseases in general.

Protein palmitoylation and lipid modifications are essential post‐translational processes that regulate protein localisation, stability and function by the covalent attachment of fatty acid chains.

Scientists have pinpointed the enzyme YcaO as responsible for a rare ribosomal protein modification in several pathogenic bacteria, a process absent in humans. The finding could open new avenues for ...

Eight histones assemble into so-called nucleosomes, around which DNA is wrapped and thereby compacted. Chemical modification of these proteins while they are being synthesized is crucial for proper ...

N-terminal acetylation represents one of the most ubiquitous protein modifications in eukaryotic cells, with significant implications for protein stability, folding, and interactions. This covalent ...

A research team led by Professor Seung Soo Oh and Dr. Hyesung Jo from the Department of Materials Science and Engineering at POSTECH (Pohang University of Science and Technology) has developed an ...

A research team led by Purdue University’s W. Andy Tao has discovered of a new type of protein modification related to cellular mutation that impairs a crucial enzyme’s ability to help drive energy ...

Neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, present a significant health challenge, affecting over 50 million people globally. One common feature of these diseases is the ...