Prion disease is a rapidly fatal and currently untreatable neurodegenerative disease. Although rare, with roughly 300 cases reported each year in the United States, it typically causes rapid ...

The work of University of Alberta researchers and their teams has contributed to an important next step in finding a cure for deadly prion-folding diseases in humans and animals. Professor Michael ...

Sonia Vallabh had already obtained her law degree from Harvard, but after her diagnosis, decided to retrain in biomedical ...

Two recent cases of prion disease in the U.S. may have been caused by contaminated deer meat, though the connection is still unproven. Reading time 3 minutes A new study might point to the first signs ...

A new epigenetic editing tool shows promise as a therapy for prion disease. The approach for silencing prion protein (PrP), is both specific and can lead to wide-spread knockdown expression of PrP ...

The National Prion Disease Pathology Surveillance Center (NPDPSC) at Case Western Reserve University will receive up to $20 million in funding as part of a grant renewal from the Centers for Disease ...

CHARM – a novel molecular tool – can turn off disease-causing genes, such as the prion protein gene. Researchers at the Broad Institute of MIT and Harvard have collaborated with the Whitehead ...

New research from Japan suggests that a rare brain-destroying disease caused by rogue prion proteins may be becoming more common—likely due to an aging population. The study, published last month in ...

Antibodies targeting the normal PrP version of the prion protein have been found in humans selected at random with no history of any associated transmissible spongiform encephalopathies. Researchers ...

Surface features of human prions responsible for their replication in the brain have been identified for the first time, which may provide key information into treatments of neurodegenerative diseases ...