Immunoglobulins (Ig) are also known as antibodies. These proteins protect the body against disease. There are many different types of Ig. Certain diseases result in the growth of an excess number of ...
Monoclonal Gammopathies (MG) are characterized by chromosomal aberration of B-cells or plasma cells resulting in benign or malignant proliferation of the affected clone. The product of such clone, a ...
Background: Diagnosis of monoclonal gammopathies (MGs) is determined by demonstration of a monoclonal immunoglobulin molecule or chain in serum and/or urine. Previous results on immunofixation ...
Two questions were asked to the five biologists: Do you consider that the monoclonal abnormality characterized at diagnosis is still present? Does the immunofixation result suggest an oligoclonal ...
Current guidelines by the International Myeloma Working Group and College of American Pathologists recommend performing serum protein electrophoresis (SPEP) and serum free light chain (sFLC) testing ...
Elevated Serum Free Light Chains Are Associated With Event-Free and Overall Survival in Two Independent Cohorts of Patients With Diffuse Large B-Cell Lymphoma Forty-three percent of patients achieved ...
Heparin-induced thrombocytopenia (HIT) is an immune-mediated platelet disorder caused by antibodies that target complexes of platelet factor 4 (PF4) and heparin. HIT has been characterized as a ...
Elevated Serum Free Light Chains Are Associated With Event-Free and Overall Survival in Two Independent Cohorts of Patients With Diffuse Large B-Cell Lymphoma Forty-three percent of patients achieved ...
Clin Lymphoma Myeloma. 2010;10(4):278-280. Our study has several limitations. Clinical information on the patients studied was incomplete, in part because half of the serum specimens came from ...