For decades, biologists assumed a cell's energy simply diffused to wherever it was needed. It turns out the most important destination of all has a private delivery line.

Back 2.8 billion years ago, while Earth shifted its plates to make new continents and violent volcanoes produced new crust, life crafted a novel invention of its own. 1,2 At first, the nucleus was ...

The image shows the cross section mutant brown adipose tissue section with enlarged lipid droplets (yellow) and nucleus (blue) being impinged by multiple mitochondria (red). Mitochondria are ...

Researchers at the Francis Crick Institute have shown that the "pacemaker" controlling yeast cell division lies inside the nucleus rather than outside it, as previously thought. Having the pacemaker ...

Alteration of the size and stiffness of the nucleus triggered by environmental cues are thought to be important for eukaryotic cell fate and function. However, it remains unclear how context-dependent ...

Nuclear mechanobiology has rapidly emerged as a transformative interdisciplinary field at the intersection of cell biology, biophysics, engineering, and materials science. This discipline focuses on ...