Modulating G protein-coupled receptors (GPCRs) is one of the major challenges in biomedicine. These are flexible proteins ...
Nature study describes a de novo protein design and high-throughput living-cell screening platform for creating miniproteins that modulate G protein-coupled receptors (GPCRs), a major class of drug ...
The year was 2022. Chris Norn, PhD, was wrapping up his time as a postdoctoral researcher at the Institute for Protein Design (IPD) at University of Washington (UW). AlphaFold was taking the field by ...
“Abalone Bio’s FAST platform’s capability to generate functionally active GPCR antibodies, presents an opportunity to push the boundaries of therapeutic antibody discovery,” said Richard Yu, PhD, ...
Our body receives and processes a vast number of signals. Chemical signals serve as guidance cues and ensure, for example, ...
This article was published in Scientific American’s former blog network and reflects the views of the author, not necessarily those of Scientific American Brian Kobilka (Stanford) and Robert Lefkowitz ...
Skape Bio and researchers at the University of Washington’s Institute for Protein Design (IPD) today announced a peer-reviewed study published in the leading international journal Nature demonstrating ...
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