Fox Sports NFL Expert Picks

NFL Week 12 Early Picks Against Spread

NFL Week 12: Picks, predictions and odds for every game

Week 12 of the 2025 NFL season kicks off on Thursday night when the Buffalo Bills visit the Houston Texans and wraps up Monday night with Christian McCaffrey's San Francisco 49ers facing off against the tailback's former franchise, the Carolina Panthers.

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2025 NFL Week 11 Best Bets, Expert Picks: Fade Uneven Bills, Packers

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NFL Week 12 picks, predictions for who wins must-win games on NFL schedule this week

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2025 NFL Week 12 passing INTs predictions and player prop bets

Looking ahead to Week 12 of the NFL regular season, which players are likely to wind up with the most passing INTs in the league?

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NFL Week 12 Predictions & Picks – Underdog Best Bets Against the Spread

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2025 NFL Week 12 rushing touchdowns predictions and player prop bets

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Colts vs. Chiefs prediction: Odds, expert picks, QB matchup, injury update, betting trends, and stats

I t comes as no surprise that Sunday's game at Arrowhead between the Kansas City Chiefs and the Indianapolis Colts features a team fighting for its playoff life against a team battling for the league's best record.

Week 12 NFL betting guide, props, spreads: Model, expert, parlay, DFS and season-long fantasy picks revealed

NFL picks, predictions, DFS advice and fantasy football rankings from SportsLine's model and team of Vegas experts