Iron catalyst drives asymmetric 1,6 addition of aliphatic Grignard reagents to α,β,γ,δ-unsaturated carbonyl compounds

Scientists at the Institute of Science Tokyo (Science Tokyo) have successfully realized the highly selective asymmetric 1,6 ...
Nature

Aldehydes as alkyl carbanion equivalents for additions to carbonyl compounds

Figure 1: Synthetic strategies to access secondary and tertiary alcohols by carbonyl addition reactions. Despite considerable advances, and the abundance of organometallic reagents developed for ...