CREB has previously been shown to be upregulated in the majority of acute leukemias, both at diagnosis and relapse. In contrast, CREB expression was found to be lower in bone marrow cells of patients ...

A breakthrough mechanism of action targeting neural plasticity associated with addiction, particularly through the CREB regulator, a key factor in relapse An educational video illustrating ...

Bipolar disorder, also known as manic-depressive illness, is a serious mental illness characterized by alternating episodes of mania and severe depression. It is one of the leading disabilities ...

Despite increasing evidence linking alcohol consumption to cancer, little is known about the biological mechanisms behind the association. A new study, published Aug. 12 in Cellular and Molecular ...

Researchers have investigated how neuronal activity influences cAMP response element binding protein (CREB) dynamics. Osaka University-led researchers investigate how neuronal activity influences cAMP ...

Scientists have designed and developed novel biosensors that allow the simultaneous study of both sensory evoked neuronal activity and transcription factor dynamics. Our brains have a remarkable knack ...

A single center retrospective cohort study of patients with metastatic breast cancer and leptomeningeal disease: Updated survival data and subgroup analyses by breast cancer subtype. Updated safety ...

Another quality of the rats interested Subhash Pandey of the University of Illinois at Chicago. "When they drink alcohol," Pandey says, "their anxiety disappears." Pandey wanted to find out what was ...

American scientists have come out with research findings they hope will aid in the treatment of Alzheimer’s patients- by saving bits of memories before they all fade off. Says lead researcher Alcino ...

Our brains have a remarkable knack for adaptability. Each and every day the neuronal connections within are constantly changing, molded by what we experience in our daily lives. The memories we make, ...