The Panthers won a 31-28 upset when these teams met in Charlotte in late November. Los Angeles is 12-5 against the spread and 10-7 to the Over. Carolina is 10-7 ATS and 10-7 to the Under. The Rams have covered four of their last five and have produced five straight Overs. The Panthers have produced four straight Unders.

The Bills have played the Jaguars in the playoffs twice and both times Buffalo's starting quarterback was knocked out of the game with a concussion.