DNA's iconic double helix does more than "just" store genetic information. Under certain conditions, it can temporarily fold ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

Dr Miglė Tomkuvienė, a senior researcher at Vilnius University, explores the issues of ageing and cell degeneration over time.

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...

DNA, though tightly packed in the nucleus, is constantly threatened by damage from metabolism and external stressors. One particularly severe form of DNA damage is the so-called DNA–protein crosslinks ...

Genome instability can cause numerous diseases. Cells have effective DNA repair mechanisms at their disposal. A research team has now gained new insights into the DNA damage response. Whenever cells ...

Scientists have discovered that a protein once thought to simply help load a factor necessary for the copying of DNA, plays a ...

A major technological advance in DNA writing enables researchers to construct and create in the language of biology ...

DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...

Although DNA is tightly packed and safeguarded within the cell nucleus, it remains continually at risk of damage from normal ...